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2020
2019
--- Joined McMaster University ---
2017
2020
- Lin, D. S. Y.; Rajasekar, S.; Marway, M. K.; Zhang, B., From Model System to Therapy: Scalable Production of Perfusable Vascularized Liver Spheroids in “Open-Top“ 384-Well Plate. ACS Biomaterials Science & Engineering 2020. View preprint; Link to Paper
- Portillo-Esquivel, L. E.; Nanduri, V.; Zhang, F.; Liang, W.; Zhang, B., z-Wire: A Microscaffold That Supports Guided Tissue Assembly and Intramyocardium Delivery for Cardiac Repair. Advanced Healthcare Materials 2020, 2000358. View View Preprint; Video S1; Video S2; Video S3; Video S4; Video S5; Video S6; Video S7; Video S8. Link to Paper.
- Xie, R.; Korolj, A.; Liu, C.; Song, X.; Lu, R. X. Z.; Zhang, B.; Ramachandran, A.; Liang, Q.; Radisic, M., h-FIBER: Microfluidic Topographical Hollow Fiber for Studies of Glomerular Filtration Barrier. ACS Central Science 2020. View PDF,
2019
- Zhang, B.; Radisic, M., Organ-level vascularization: The Mars Mission of Bioengineering. The Journal of Thoracic and Cardiovascular Surgery 2019. View PDF
- Parrish, J.; Lim, K.; Zhang, B.; Radisic, M.; Woodfield, T. B. F., New Frontiers for Biofabrication and Bioreactor Design in Microphysiological System Development. Trends in Biotechnology, 2019. View PDF
- Yimu Zhao.; Wang, E.Y.; Huyer, L.D.; Liao, S.; Yeager, K; Vunjak-Novakovic, G.; Radisic, M.; Boyang Zhang, A multimaterial microphysiological platform enabled by rapid casting of elastic micro-wires. Advanced Healthcare Materials, 2019. View PDF
- Yimu Zhao, Naimeh Rafatian, Nicole T. Feric, Brian J. Cox, Roozbeh Aschar-Sobbi, Erika Yan Wang, Praful Aggarwal, Boyang Zhang, Genevieve Conant, Kacey Ronaldson-Bouchard, Aric Pahnke, Stephanie Protze, Jee Hoon Lee, Locke Davenport Huyer, Danica Jekic, Anastasia Wickeler, Hani E. Naguib, Gordon M. Keller, Gordana Vunjak-Novakovic, Ulrich Broeckel, Peter H. Backx, Milica Radisic, A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling, Cell, 2019. View PDF
- Dawn S. Y. Lin, Feng Guo, Boyang Zhang, Modeling organ-specific vasculature with organ-on-a-chip devices, Nanotechnology, 2018. View PDF
- Anastasia Korolj, Carol Laschinger, Chris James, Erding Hu, Claire Velikonja, Nathaniel Smith, Irene Gu, Samad Ahadian, Robert Willette, Milica Radisic and Boyang Zhang, Curvature facilitates podocyte culture in a biomimetic platform, Lab on a Chip, 2018. View PDF
- Boyang Zhang , Benjamin Fook Lun Lai, Ruoxiao Xie, Locke Davenport Huyer, Miles Montgomery, Milica Radisic, Microfabrication of AngioChip, a biodegradable polymer scaffold with microfluidic vasculature, Nature Protocol, 2018. View PDF
- Boyang Zhang, Anastasia Korolj, Benjamin Fook Lun Lai, Milica Radisic, Advances in organ-on-a-chip engineering. Nature Reviews Materials, 2018. View PDF
--- Joined McMaster University ---
2017
- Kacey Ronaldson, Nicole Feric, Yimu Zhao, Boyang Zhang , Genna Conant, Aric Panhke, Roozbeh Aschar-Sobbi, Gordana Vunjak-Novakovic, Peter Backx, Milica Radisic, TARA Biosystems' BiowireTM II: Engineering Mature Human Cardiac Tissues Enables More Predictive Drug Screening, Journal of Pharmacological and Toxicological Methods, 2017. View PDF
- Takebe T., Zhang B., Radisic M., Synergistic Engineering: Organoids meets Organs-on-a-Chip, Cell Stem Cell, 2017. View PDF
- Lai B., Davenport L., Lu R., Drecun S., Radisic M., Zhang B., InVADE: Integrated Vasculature for Assessing Dynamic Events. Advanced Functional Materials, 2017. View PDF
- Ahadian S., Civitarese R., Bannerman D., Mohammadi M., Rick L., Wang Y., Huyer L., Lai F., Zhang B., Zhao Y., Mandla S., Korolj A., Radisic, M., Organ-on-a-chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies, Advanced Healthcare Materials, 2017. View PDF
- Zhang B., Radisic M., Organ-on-a-Chip devices advance to market. Lab on a Chip, 2017. View PDF
- Massé S., Magtibay K., Jackson N., Asta J., Kusha M., Zhang B., Balachandran R, Radisic M., Deno D. C., and Nanthakumar K. Resolving myocardial activation with novel omnipolar electrograms. Circulation – Arrhythmia and Electrophysiology. 2016. View PDF
- Davenport Huyer L, Zhang B, Korolj A, Montgomery M, Drecun S, Conant G, Zhao Y, Reis L, Radisic M. A highly elastic and moldable polyester biomaterial for cardiac tissue engineering applications. ACS Biomaterials Science & Engineering. 2016. View PDF
- Zhang B, Montgomery M, Chamberlain M.D., Ogawa S., Korolj, A., Pahnke A, Wells L.A., Massé S, Kim J, Reis L, Abdulah M, Nunes S.S., Nanthakumar K, Gordon, K., Sefton M.V., Radisic M. Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis. Nature Materials (Featured on the cover). 2016. View PDF, Supplementary Doc, Movie S1, Movie S2, Movie S3, Movie S4, Movie S5, Movie S6, Movie S7.
- "AngioChip" highlighted in:
- Nature Reviews Materials, "Tissue engineering: A hearty chip", 2016. View PDF
- Toronto Star, "U of T researchers develop homegrown human on a chip", 2016.
- CBC The National, "Beating 'heart on a chip' developed by Canadian scientists", 2016.
- Yahoo News, "3-D heart, liver tissues that function like real organs grown", 2016.
- "AngioChip" highlighted in:
- Zhang B, Montgomery M, L Davenport-Huyer, A Korolj, Radisic M. Platform technology for scalable assembly of instantaneously functional mosaic tissues. Science Advances. 2015; 1 (7), e1500423. View PDF
- "Tissue Velcro" highlighted in:
- Popular Science, "Synthetic Heart Tissue Sticks Like Velcro", 2015.
- MotherBoard Vice, "This Lab-Grown Tissue Snaps Together Like Velcro", 2015.
- New Scientist, "Live cells stuck together like Velcro could mend broken hearts", 2015.
- The Scientist, "Next Generation: Cell-Covered Fastener", 2015.
- "Tissue Velcro" highlighted in:
- Montgomery M, Zhang B (co-first author), Radisic M. Cardiac Tissue Vascularization: from Angiogenesis to Microfluidic Blood Vessels. Journal of Cardiovascular Pharmacology and Therapeutics. 2014; 1074248414528576. View PDF
- Miklas JW, Nunes SS, Zhang B, Radisic M. Design and fabrication of biological wires. Cardiac Tissue Engineering: Methods and Protocols. 2014; 157-165. View PDF
- Dang LT, Feric NT, Laschinger C, Chang WY, Zhang B, Wood GA, Stanford WL, Radisic M. Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS. Biomaterials. 2014; 35 (27), 7786-7799. View PDF
- Xiao Y, Zhang B, Liu H, Miklas JW, Gagliardi M, Pahnke A, Thavandiran N, Sun Y, Simmons C, Keller G, Radisic M. Microfabricated perfusable cardiac biowire: a platform that mimics native cardiac bundle. Lab on a Chip (Cover article). 2014; 14 (5), 869-882. View PDF
- Zhang B, Peticone C, Murthy SK, Radisic M. A standalone perfusion platform for drug testing and target validation in micro-vessel networks. Biomicrofluidics. 2013; 7 (4), 044125. View PDF
- Nunes S, Miklas JW, Liu J, Aschar-Sobbi R, Xiao Y, Zhang B, Jiang J, Massé S, Gagliardi M, Hsieh A, Thavandiran N, Laflamme MA, Nanthakumar K, Gross GJ, Backx PH, Keller G, Radisic M. Biowire: a platform for maturation of human pluripotent stem cell–derived Cardiomyocytes. Nature Methods. 2013; 10 (8), 781-787. View PDF
- "Biowires" highlighted in:
- The Science Daily, "New 'biowire' technology matures human heart by mimicking fetal heartrate", 2013.
- "Biowires" highlighted in:
- Martin C, Sofla A, Zhang B, Nunes S, Radisic M. Fusible core molding for fabrication of branched three-dimensional perfusable microvessels for vascular tissue engineering. International Journal of Artificial Organs. 2013; 36 (3), 159-165. View PDF
- Leng L, McAllister A, Zhang B, Radisic M, Günther A. Mosaic hydrogels: Dynamic tessellation and coding. Advanced Materials (Cover Article), 2013; 24 (27), 3650-3658. View PDF
- Tandon V, Zhang B, Radisic M, Murthy SK. Generation of Tissue Constructs for Cardiovascular Regenerative Medicine: From Cell Procurement to Scaffold Design. Biotechnology Advances, 2013; 31 (5), 722-735. View PDF
- Zhang B, Green J, Murthy S, Radisic M. Label-free enrichment of functional cardiomyocytes using microfluidic deterministic lateral flow displacement. Plos-One. 2012; 7 (5), e37619. View PDF
- Zhang B, Xiao Y, Hsieh A, Thavandiran N, Radisic M. Micro and nanotechnology in cardiovascular tissue engineering. Nanotechnology. 2011; 22 (49), 494003. View PDF
- Hirsch A, Rivet CA, Zhang B, Kemp ML and Lu H. Parallel Multi-time Point Cell Stimulation and Lysis on-chip for Studying Early Signaling Events in T Cell Activation. Lab on a Chip. 2009; 9 (4), 536-544. View PDF